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Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Model Organisms Mouse While Drosophila melanogaster has a very short life cycle and is very cheap to keep alive thousands of samples, mouse is the closest best studied organism to us, humans. The mo...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
06-23-2014, 06:22 AM
Thread: Lysosomal Storage Disorder and its Treatment
Post: RE: Lysosomal Storage Disorder and its Treatment
Schindler disease Named after Detlev Schindler who discovered it, this disease is also known as Kanzaki disease, named after Japanese scientist Hiro Kanzaki who gave additional details about the dise...
Author: zemaxe7
Forum: Genetic Engineering
6 25,772
06-22-2014, 11:29 PM
Thread: Lysosomal Storage Disorder and its Treatment
Post: RE: Lysosomal Storage Disorder and its Treatment
Farber disease Discovered by Sidney Farber, this disease is characterized by mutations in ASAH1 gene coding for an enzyme acid ceramidase which catalyzes the synthesis and degradation of ceramide (wa...
Author: zemaxe7
Forum: Genetic Engineering
6 25,772
06-22-2014, 09:04 PM
Thread: Lysosomal Storage Disorder and its Treatment
Post: RE: Lysosomal Storage Disorder and its Treatment
Lysosomal Storage Diseases Glycogen Storage Disease II This disease is characterized by the deficiency of the lysosomal acid alpha-glucosidase enzyme. It is also known by two other names: Pompe dise...
Author: zemaxe7
Forum: Genetic Engineering
6 25,772
06-22-2014, 04:48 AM
Thread: Lysosomal Storage Disorder and its Treatment
Post: RE: Lysosomal Storage Disorder and its Treatment
Lysosomal Storage Diseases Tay-Sachs disease This disease is caused by mutations on HEXA gene on our chromosome 15. HEXA gene encodes for one part of lysosomal enzyme beta-N-acetylhexosaminidase A. ...
Author: zemaxe7
Forum: Genetic Engineering
6 25,772
06-21-2014, 10:49 PM
Thread: Techniques of Genetic Engineering
Post: RE: Techniques of Genetic Engineering
Hybrid Vectors Plasmids and phages are “regular” types of vectors that have not been heavily modified. However, the advancements in our technology and the need for more complex genetic experiments ha...
Author: zemaxe7
Forum: Genetic Engineering
9 123,739
06-20-2014, 11:16 PM
Thread: Techniques of Genetic Engineering
Post: RE: Techniques of Genetic Engineering
Vectors Based on Bacteriophage M13 Phage M13 has some advantages but also some disadvantages concerning the usage for genetic experiments and based on them, it should be chosen only in some cases. T...
Author: zemaxe7
Forum: Genetic Engineering
9 123,739
06-18-2014, 03:37 AM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
LncRNA – Long non-coding RNA As their name suggests, lncRNA molecules are a bit longer transcripts when compared to miRNAs, siRNAs, snoRNAs, etc. (longer than 200 nucleotides) and they do not code fo...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
06-18-2014, 02:25 AM
Thread: Techniques of Genetic Engineering
Post: RE: Techniques of Genetic Engineering
Vectors Based on Bacteriophage Lambda Lambda phage can be used in genetic experiments as a vector because not all of its genome is essential for its function. This allows for the introduction of new ...
Author: zemaxe7
Forum: Genetic Engineering
9 123,739
06-17-2014, 03:48 AM
Thread: Techniques of Genetic Engineering
Post: RE: Techniques of Genetic Engineering
Bacteriophage Vectors Bacteriophages are basically bacterial viruses (eaters of bacteria), and they usually consist out of DNA genome enclosed in a protein head, also known as capsid, made out of pro...
Author: zemaxe7
Forum: Genetic Engineering
9 123,739
06-17-2014, 02:08 AM
Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Arabidopsis thaliana Arabidopsis thaliana is the best studied organism among plants. In fact, I think it is one of the three most studied organisms overall (not including humans, the other two are Dr...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
06-17-2014, 12:56 AM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
SnoRNA – Small Nucleolar RNA Small nucleolar RNAs also fall into the category of small RNA molecules. Their main function is related to the chemical modification of other RNA molecules and based on t...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
06-16-2014, 07:35 PM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
RasiRNA – repeat associated small interfering RNA As the name itself suggests, rasiRNAs are involved in the RNAi pathway (RNA interference). They are actually a subclass of piRNAs (piwi-interacting R...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
06-15-2014, 11:00 PM
Thread: Unusual chromosomes and their properties
Post: RE: Unusual chromosomes and their properties
The New Yeast Artificial Chromosome - SynIII Scientists have managed to synthesize completely new chromosome from one of yeast’s 16 chromosomes. Namely, the team from the Langone Medical Centre at Ne...
Author: zemaxe7
Forum: Gene and Cell therapy
6 30,006
06-15-2014, 09:55 PM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
PiRNA – piwi-interacting RNA PiRNAs form the largest class of small non-coding RNA molecules and they got their name because of the complexes they form with piwi proteins (RNA-protein complexes). The...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
06-15-2014, 07:50 PM
Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Fruit Fly – Drosophila melanogaster Fruit fly is definitely one of the best studied model organisms. I even like to think of it as a model organism among model organisms. The reason for this lies in ...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
06-15-2014, 07:43 PM
Thread: Unusual chromosomes and their properties
Post: RE: Unusual chromosomes and their properties
How about the entire genome? Instead of creating only one artificial chromosome, scientists have actually managed to synthesize the entire genome of bacteria. A team of scientists from the J. Craig V...
Author: zemaxe7
Forum: Gene and Cell therapy
6 30,006
06-15-2014, 07:39 PM
Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Model Organisms Roundworm (Caenorhabditis elegans) C. elegans is in the group of nematode worms (they are basically unsegmented worms with elongated rounded body pointed at both ends) and it is grea...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
06-01-2014, 12:50 AM
Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Yeast (Saccharomyces cerevisiae) The yeast is perfect for genetic studying and engineering because it has the cellular organization of a eukaryote, but it is pretty simple single-celled organism that...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
05-12-2014, 06:28 PM
Thread: The Most Fascinating Examples of Genetic Engineering
Post: RE: The Most Fascinating Examples of Genetic Engin...
Model Organisms While there are some specific interesting examples of genetic engineering done on some organisms, there are organisms that have been extensively experimented on, due to their relative...
Author: zemaxe7
Forum: Genetic Engineering
7 52,933
05-12-2014, 01:58 PM
Thread: Preserve Species by Changing their Genetic Structure
Post: RE: Preserve Species by Changing their Genetic Str...
Revival of the species – Mammoth Another goal of the Long Now foundation is to revive the mammoth. They have been extinct for some five thousand years now and a lot of scientists would like to see th...
Author: zemaxe7
Forum: Genetic Engineering
9 45,404
05-12-2014, 01:55 PM
Thread: Preserve Species by Changing their Genetic Structure
Post: RE: Preserve Species by Changing their Genetic Str...
Revival of the species – Passenger Pigeon Project “Revive & Restore” from Long Now foundation is all about de-extinction. Their first goal is to revive the famous passenger pigeon, which has been...
Author: zemaxe7
Forum: Genetic Engineering
9 45,404
05-09-2014, 03:42 AM
Thread: Preserve Species by Changing their Genetic Structure
Post: RE: Preserve Species by Changing their Genetic Str...
Revival of the species – The Beginning The animal revival has actually already been done. In 2003, a group of Spanish and French scientists have revived a goat bucardo that lived in the Pyrenees. It ...
Author: zemaxe7
Forum: Genetic Engineering
9 45,404
05-08-2014, 07:10 PM
Thread: Preserve Species by Changing their Genetic Structure
Post: BUILDING HOPE: Regeneration on a nature's platform
Revival of the species Another way of preserving the species is actually by reviving them. There is a lot of controversy around this - some people are saying that the resources spent into the revival...
Author: zemaxe7
Forum: Genetic Engineering
9 45,404
05-07-2014, 10:59 PM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
Other RNA types SiRNA – small interfering RNA Small interfering RNA molecules are another type of short RNA molecules that can silence some genes by targeting them for degradation. SiRNAs were disco...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
05-07-2014, 03:52 AM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
Other RNA types MiRNA – micro RNA These are small non-coding RNA molecules (usually about 22 nucleotides long), and their main function is transcriptional and post-transcriptional regulation of gene...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
05-05-2014, 08:19 PM
Thread: Unusual chromosomes and their properties
Post: RE: Unusual chromosomes and their properties
Types of artificial chromosomes HAC – Human artificial chromosome Human artificial chromosome was constructed from scratch during the 1990s in human fibrosarcoma cell line (fibrous connective tissue...
Author: zemaxe7
Forum: Gene and Cell therapy
6 30,006
05-02-2014, 02:21 PM
Thread: Scientists Created Mosquitoes That Cannot Transmit Malaria
Post: RE: Scientists Created Mosquitoes That Cannot Tran...
Another interesting way malaria cannot be transmitted There is another “natural” way, or condition which prevents the spreading of Malaria – it is the sickle-cell disease! Sickle-cell anemia is cong...
Author: zemaxe7
Forum: Genetic Engineering
3 17,608
05-02-2014, 01:48 AM
Thread: Formation and Characteristics of tRNA, rRNA and mRNA
Post: RE: Formation and Characteristics of tRNA, rRNA an...
Other RNA types SnRNA – small nuclear RNA These are short RNA molecules (around 150 nucleotides in length) found in the nucleus of eukaryotic cells. They were actually discovered by accident in the ...
Author: zemaxe7
Forum: Genetic Engineering
9 94,625
05-01-2014, 10:04 PM
Thread: Unusual chromosomes and their properties
Post: RE: Unusual chromosomes and their properties
Types of artificial chromosomes BAC – Bacterial artificial chromosome This is another popular artificial chromosome used in genetic engineering. The main difference between it and the yeast artifici...
Author: zemaxe7
Forum: Gene and Cell therapy
6 30,006
05-01-2014, 02:29 PM