03-05-2017, 03:10 AM
(03-05-2017, 03:05 AM)RahulK Wrote:Cytochalisin is not "ONLY" inhibitor if reported in literature. Even one eukaryotic is evidence that cilchicin can "ALSO" be used. So in such cases either marks should be given to all or question cancel.(03-05-2017, 01:40 AM)masthanbasha Wrote: yes Rahul u can and the debasmita explanation was also correct
Actually the problem is that colchicine along with other options in question, Vinbalstine, nocodazole are all inhibitors of microtubule formation which inhibits mitosis, thus all three are mitotic inhibitors reported in Gerald karp book and other sources. Cytochalasin D in small concentrations inhibits the formation of actin filaments which directly inhibits the cytokinesis.
I have only a couple of research papers which have reported cytokinesis inhibition with colchicine, that might not be enough to support our challenge. Still I will give a try.