[bvs science freak]

Hi,I'm new to this forum. .But i'm A biotech student..Wishing all will help me to enrich myself with all your knowledge..Thanks for all..I'm a student for all those who enriches my knowledge..

I know that laminar air flow cabinets of various safety levels are used for handling infectious microbes or micro-organisms..

Please any one help me to know how they worked with deadliest or infectious microbes in early age when the technological development is low ?or if laminar air flow cabinet can't b used in a situation,how sterile mico-organism cultures can be made?