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Diabetes: Symptoms, Treatment and Latest Research
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FDA has very recently issued a warning on the use of SGLT2 inhibitors that are suspected to be linked to the fatal condition called KETOACIDOSIS.

SGLT-2 inhibitors (sodium-glucose cotransporter-2 inhibitors) like Canagliflozin, Dapagliflozin and Empagliflozin are reported to elevate blood ketones levels, which can lead to diabetic coma or even death!

Some brand names of these drugs include:
  • Invokana (canagliflozin)
  • Glyxambi (empagliflozin and linagliptin)
  • Farxiga (dapagliflozin)
  • Invokamet (canagliflozin and metformin)
  • Xigduo XR (dapagliflozin and metformin)
  • Jardiance (empagliflozin)

It is thus advised to patients of Type-2 diabetes to monitor their ketone levels (ketoacidosis) regulary while consuming SGLT-2 inhibitors. Symptoms like difficulty breathing, nausea, vomiting, abdominal pain, unusual fatigue or sleepiness, confusions should be immediately addressed.

Best wishes
Sunil Nagpal
MS(Research) Scholar, IIT Delhi (Alumnus)
Advisor for the Biotech Students portal (BiotechStudents.com)
Computational Researcher in BioSciences at a leading MNC


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FDA warns about Type-2 Diabetes drugs - by SunilNagpal - 05-19-2015, 06:16 PM
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