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Diabetes: Symptoms, Treatment and Latest Research
A preventive and curative vaccine for type-1 diabetes has been claimed by a team of Spanish scientists. The team belonging to Universitat Autonoma de Barcelona (Spain) has used the very familiar "Liposomes" for imitating the apoptotic beta-cells of pancreas, thereby preventing the self-destruction of the beta-cells by the body.

Earlier, the dendritic cells (immune cells) of the subjects used to be extracted and subsequently manipulated and re-injected into the subjects to avoid the destruction of the insulin-producing pancreatic cells (beta cells) in the body. 

The Liposome mediated prevention of type-1 diabetes has been currently tested on mice and is all-set to be tested in Humans through clinical trials.

Following figure gives an idea of the findings in nutshell (taken from the publicly available paper at PLOS ONE):
Cumulative incidence (percentage) of T1D in NOD mice treated with PSAB-liposomes (PSAB-lipo, circles, n = 12), PS-liposomes (PS-lipo, squares, n = 18), and sham group (triangles, n = 26). Significant differences were found when compared group treated with PSAB-liposomes versus sham group (*p≤0.05, Kaplan-Meier log-rank analysis).

Full paper on this research may be referred to in PLOS ONE.
Link to paper:
Sunil Nagpal
MS(Research) Scholar, IIT Delhi (Alumnus)
Advisor for the Biotech Students portal (
Computational Researcher in BioSciences at a leading MNC

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Vaccine to Cure Type-1 Diabetes ! - by SunilNagpal - 06-10-2015, 10:57 PM
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