[SunilNagpal]

Hi Kanny,

In general, molecular weight range in case of RP should be associated with 'pore size' of the column (larger peptides would need a wider column, while smaller peptides may be dealt with a narrow one as well). Since it's not a 'molecular sieve' chromatography, the stationary phase (C18) should be expected to have a universal range.

At the same time, it would be an interesting piece of information, as to what's the 'handling limit' of C18 stationary phase in general.