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GATE BT-2017 Answer Key | Solutions Discussion
(02-28-2017, 10:04 PM)CHANDA7 Wrote:
(02-28-2017, 09:22 PM)SunilNagpal Wrote: [Image: 6931eb92a4b04caf864f8031fc9dba2d.jpg]
(Right now in a train going back to my home town so pardon the lack of figurative explanation , but i will try my best to put my point of view to the pedigree question. I hope this is the question which everyone is talking about?

To me option B seems the right answer (it can either be an X linked recessive one or only Y linked). Both cases hold good for the given pedigree.

Only Y linked is evidently very much applicable in the entire scenario and hence this is definitely there. Now the problem I see is that most of you are overlooking the fact that the mothers can be non-carriers as well.

xx - Xy (where X is the carrier chromosome) is very much possible in entire pedigree and if the disease is X linked recessive, females will not be affected in the given pedigree.

Will explain further as and when you guys place counter arguments to this case...
Sir,
In this case the male individuals of the first generation will not be affected, because their x chromosome comes from mother and none of them is affected....
(02-28-2017, 09:22 PM)SunilNagpal Wrote: [Image: 6931eb92a4b04caf864f8031fc9dba2d.jpg]
(Right now in a train going back to my home town so pardon the lack of figurative explanation , but i will try my best to put my point of view to the pedigree question. I hope this is the question which everyone is talking about?

To me option B seems the right answer (it can either be an X linked recessive one or only Y linked). Both cases hold good for the given pedigree.

Only Y linked is evidently very much applicable in the entire scenario and hence this is definitely there. Now the problem I see is that most of you are overlooking the fact that the mothers can be non-carriers as well.

xx - Xy (where X is the carrier chromosome) is very much possible in entire pedigree and if the disease is X linked recessive, females will not be affected in the given pedigree.

Will explain further as and when you guys place counter arguments to this case...
Perfectly right, female non carrier thing is not needed here. Thanks for correcting me. Even if the first mother is a carrier, isn't there always a possibility to have carrier only female progenies? I mean birth of each son/ daughter is an isolated event and there always exists a possibility of unaffected females by being a carrier...
Sunil Nagpal
MS(Research) Scholar, IIT Delhi (Alumnus)
Advisor for the Biotech Students portal (BiotechStudents.com)
Computational Researcher in BioSciences at a leading MNC


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Messages In This Thread
A GATE BT Marks Survey Page - by reviewer21 - 02-28-2017, 05:31 AM
RE: A GATE BT Marks Survey Page - by SunilNagpal - 03-01-2017, 02:09 AM
RE: A GATE BT Marks Survey Page - by CHANDA7 - 02-28-2017, 04:37 PM
RE: GATE BT-2017 Answer Key | Solutions Discussion - by SunilNagpal - 02-28-2017, 10:13 PM
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